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Roman S Shapoval's avatar

I first found out about Bacillus subtilus when reading GAPS by Natasha McBride...a critical life form! FYI melatonin is also made in the skin aka subcellular. But yes I was also floored to learn how much we produce in the gut, I think it's like 400x more.

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Jennifer Depew, R.D.'s avatar

Thanks, Roman. Wild fermented foods likely have some Bacillus species, home sauerkraut type of pickles.

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Phar Percheron's avatar

Cool! how is melatonin made in the skin? I spend a lot of time with my heat lamps... can always use one more reason to do so...

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Roman S Shapoval's avatar

Hi Phar! Thanks for asking, that's great you're taking your health so seriously. Here's an article I wrote on that: https://romanshapoval.substack.com/p/oralmelatonin

Wat kind of red light lamps do you use?

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Jennifer Depew, R.D.'s avatar

I replied to your article and will copy it here: Melatonin taken in the morning with flush niacin may support mitochondrial health without causing circadian cycle disruption. Larger amounts spaced during the day of melatonin was found to have some anti-CoV potential (lots ~ 600 mg, taken as five evenly spaced doses (120 mg) during the day, not for 'sleep' purposes - mitochondrial support or antimicrobial/anti-inflammatory. // related references 1) https://pmc.ncbi.nlm.nih.gov/articles/PMC5387000/ 2) https://pubmed.ncbi.nlm.nih.gov/18289175/ 3) review article on CoV topis: https://pmc.ncbi.nlm.nih.gov/articles/PMC8190272/ // I use melatonin and niacin in the morning and day, 2 or maybe 3 times. My genetics lean schizophrenia though and the higher niacin use seems to help that patient subgroup.

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Phar Percheron's avatar

Excellent article. Good info. thanks.

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Roman S Shapoval's avatar

Thank you Phar for taking the time to read and appreciate!

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Phar Percheron's avatar

Heat lamps from the hardware store .. but I recently purchased some hi-tech red / infra red leg wrap thingies for neuropathy... it's a little awkward using them on other body parts. I will take a look at your article - thanks!

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Phar Percheron's avatar

Not finished reading, but the information about *supplemental * melatonin could be really just what I needed at the moment.

I have some powdered pomegranate peel, I haven't been using it because I hadn't found a convenient way to eat it. But I just tried putting some in my coffee and that seems okay. Especially since I've taken up drinking a lot of decaf coffee to mix stuff into like collagen...

The information about gut bacteria is really important to me, as I have been struggling with a little bit of heartbreak, and I find that the severity of the heartbreak is directly correlated with gut health. Before I got covid of the tummy I could feel happy hormones being generated in my tummy, trying to get back to that, but it's been a long time.

To the point where I was actually having angina symptoms, shortness of breath and all that, along with the pain in my heart... and I discovered that a microbial byproduct of carnitine metabolism ( TMAO) could hurt your heart. Synergistically with emotional heartbreak!? So now red meat is off the menu for the duration...

Just to be clear, nothing actually tragic has happened in my life, it was just a romantic misstep. It's not like my pet died or something, which would be cause for serious heartbreak!

So I'm saving your post for serious study....

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