Sounds and lights in hospitals or computer screen brightness can cause overgrowth of normal species that become an 'infection' when out of balance with good species.
Centenarian Secret Unveiled: Gut Viruses May Bolster Immunity Against Pathogens
Fresh insights propose that individuals living to a hundred or beyond — known as centenarians — harbor a wide array of viruses in their gut microbiome that may bolster their resilience against infectious diseases.
The study, unveiled today in the journal Nature Microbiology, elucidates some of the biological mechanisms potentially contributing to the longevity and robust health of centenarians.
The research, spearheaded by Joachim Johansen, Ramnik Xavier, Simon Rasmussen, and Damian Plichta at the Broad Institute of MIT and Harvard, delved into the viromes — the viral genetic material — of 195 participants from Japan and Sardinia. The results revealed that centenarians exhibit a richer diversity of gut microbiota, including bacteria and viruses.
Moreover, the team discovered that viruses prevalent in centenarians bolstered the capacity of beneficial gut bacteria to metabolize sulfate, a process that could enhance the gut's innate defenses against bacterial infections.
This study contributes to the burgeoning knowledge affirming the critical role of the dynamic interplay among bacteria, viruses, and fungi within the gut microbiome in warding off age-related ailments.
Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan
A Groundbreaking Study From Stanford University School of Medicine: The Missing Microbes From Industrialized Populations Were Finally Found!
MY SUMMARY
In an unprecedented study published in Cell Press, the couple Sonnenburg analyzed the gut microbiomes of 167 Hadza hunter-gatherers from Tanzania.
The researchers conducted ultra-deep metagenomic sequencing on 351 fecal samples from the Hadza community, as well as comparative populations in Nepal and California.
Top highlights of the study:
🔹The Hadza displayed significantly higher gut microbial diversity, with an average of 730 species per person, compared to 277 species in Californians and an intermediate number in Nepali individuals.
🔹The Hadza microbiomes contained unique species, such as Treponema succinifaciens, which were absent or declining in the other populations due to industrialization.
🔹The study revealed 124 gut-resident species that are vanishing in industrialized populations!
MY THOUGHTS
Almost a week ago I shared a post with the title "50% Of The Gut Microbes In Our Primate Ancestors Deserted Us!" (1).
There was an interesting thought from Dr. Daniel Sanders:
"Maybe we need to harvest from groups that have the most diverse and beneficial microbiomes-grow them and keep a bank of them for further study. Eventually, maybe even a small pilot re-seeding project once we are 1000% sure it’s safe."
This was my reply back then to him:
"Dr. Daniel Sanders there are some studies that showed that the microbiomes of Hunter-gatherer tribes are more diverse compared to those who live in the city. There is also evidence of the diversity of the gut biome of centenarians. Maybe we can collect them... however, growing them without losing diversity is a very big task...more importantly, since we already lost 50% of them...our gut may refuse them as the whole ecosystem is different now! But it's worth the shot!"
Did I read the future of today's post? Maybe! Should we really go and "mess" with the Hunter-gatherer's microbiome to save ours? Maybe not!
HAPPY To Hear Your THOUGHTS and Stay POSITIVE!
Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes
Gardening was my first love, and I took into prenatal counseling as a career. If we want to know why 50% of our microbiome diversity "deserted" us, we should lookat what the Hadza people are eating. Our gut microbes depend on us as menu planners, and when our menu planning is bad, their growth is going to fail.
You,ve done a brilliant substack Jennifer I will keep this, thank you.
I eat only organic, keep some dirt/earth on it when cooking it. I’m a country type of person and a lot more healthy than a lot of people who spoil their bodies, microbiome , and their mind. I love nature, the rain, mud, I never wear shoes unless I have to, walk in country every day forest bathing, sometimes take the shoes off that I wore to drive there and walk bare foot even in the rain. I love gardening also, growing things watching the seasons change. Gods earth.
No sunglasses, I wear baseball cap, incandescent lights mostly, open windows, no chemicals in home (homemade stuff), no aerosol cans allowed, no TV now or for a great deal of my life can’t stand being anywhere with one.
Neem, zeolite, propolis toothpaste and mouthwash (mouth microbiome). No drugs, no alcohol.
I’m on the list for Dr Sabine Hazan’s list for microbiome control group.
Our internal "garden" menu planning is more dependent on the light signals, than the macromolecules. This is where team carnivore vs team plantbased fall down in the long-term.😉
From my menu planning perspective, I forgot to mention resistant starches as the other key food for butyrate species. I mentioned zinc.
The Carnivore diet is great for zinc but might be low in resistant starches.
The plant based diet might be lower in zinc and it might get bound up to plant chemicals. It would be good in resistant starch though. The gut microbes want quite a sizeable amount. Not a capsule supplement- macronutrient bulk.
Neither diet might have good butyrate producing species - given good lighting for both groups - in a hypothetical controlled experiment.
Interestingly, there were some issues with the Hadza studies design and data interpretation. But a big variable not accounted for is the light exposure. Microbial communities within the human body are also dependent on the sunlight via our belly being exposed at varying times during the day. Think chlorophyll in plants, likewise the microbes in our bodies synthesize all sorts of metabolites based on light signals.😉
Dang, the title.... I had noticed that I had made a mistake, and double checked all the video mentions in the post and forgot to look at the title. thanks for mentioning it Solo.
Aʟᴢʜᴇɪᴍᴇʀ Exᴘᴇʀᴛ & Bʀᴀɪɴ Mɪᴄʀᴏʙɪᴏᴍᴇ Exᴘᴇʀᴛ
🦠ʙʀɪᴅɢɪɴɢ ᴘʀᴏʙɪᴏᴛɪᴄꜱ ᴀɴᴅ ᴀʟᴢʜᴇɪᴍᴇʀ'ꜱ ʀᴇꜱᴇᴀʀᴄʜ🧠
Frank Bernier, PhD, MSc, CIP
https://www.linkedin.com/posts/francois-bernier-phd_centunarian-microbiome-diversity-activity-7064043227506491392-36K_
Centenarian Secret Unveiled: Gut Viruses May Bolster Immunity Against Pathogens
Fresh insights propose that individuals living to a hundred or beyond — known as centenarians — harbor a wide array of viruses in their gut microbiome that may bolster their resilience against infectious diseases.
The study, unveiled today in the journal Nature Microbiology, elucidates some of the biological mechanisms potentially contributing to the longevity and robust health of centenarians.
The research, spearheaded by Joachim Johansen, Ramnik Xavier, Simon Rasmussen, and Damian Plichta at the Broad Institute of MIT and Harvard, delved into the viromes — the viral genetic material — of 195 participants from Japan and Sardinia. The results revealed that centenarians exhibit a richer diversity of gut microbiota, including bacteria and viruses.
Moreover, the team discovered that viruses prevalent in centenarians bolstered the capacity of beneficial gut bacteria to metabolize sulfate, a process that could enhance the gut's innate defenses against bacterial infections.
This study contributes to the burgeoning knowledge affirming the critical role of the dynamic interplay among bacteria, viruses, and fungi within the gut microbiome in warding off age-related ailments.
Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan
https://www.nature.com/articles/s41564-023-01370-6
Very interesting
Slow sulfate metabolism is a common problem among autism. Methylation gene differences can decrease it.
😉💯👍👏👏👏🎯
Dr. Amine ZORGANI
On a Mission to SAVE the Human Microbiome from Extinction | Inventor | Speaker | Author | Producer
https://www.linkedin.com/posts/amine-zorgani_mysummary-mythoughts-myinspiration-activity-7078975172656943104-dPAh
A Groundbreaking Study From Stanford University School of Medicine: The Missing Microbes From Industrialized Populations Were Finally Found!
MY SUMMARY
In an unprecedented study published in Cell Press, the couple Sonnenburg analyzed the gut microbiomes of 167 Hadza hunter-gatherers from Tanzania.
The researchers conducted ultra-deep metagenomic sequencing on 351 fecal samples from the Hadza community, as well as comparative populations in Nepal and California.
Top highlights of the study:
🔹The Hadza displayed significantly higher gut microbial diversity, with an average of 730 species per person, compared to 277 species in Californians and an intermediate number in Nepali individuals.
🔹The Hadza microbiomes contained unique species, such as Treponema succinifaciens, which were absent or declining in the other populations due to industrialization.
🔹The study revealed 124 gut-resident species that are vanishing in industrialized populations!
MY THOUGHTS
Almost a week ago I shared a post with the title "50% Of The Gut Microbes In Our Primate Ancestors Deserted Us!" (1).
There was an interesting thought from Dr. Daniel Sanders:
"Maybe we need to harvest from groups that have the most diverse and beneficial microbiomes-grow them and keep a bank of them for further study. Eventually, maybe even a small pilot re-seeding project once we are 1000% sure it’s safe."
This was my reply back then to him:
"Dr. Daniel Sanders there are some studies that showed that the microbiomes of Hunter-gatherer tribes are more diverse compared to those who live in the city. There is also evidence of the diversity of the gut biome of centenarians. Maybe we can collect them... however, growing them without losing diversity is a very big task...more importantly, since we already lost 50% of them...our gut may refuse them as the whole ecosystem is different now! But it's worth the shot!"
Did I read the future of today's post? Maybe! Should we really go and "mess" with the Hunter-gatherer's microbiome to save ours? Maybe not!
HAPPY To Hear Your THOUGHTS and Stay POSITIVE!
Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes
https://www.cell.com/cell/fulltext/S0092-8674(23)00597-4
Gardening was my first love, and I took into prenatal counseling as a career. If we want to know why 50% of our microbiome diversity "deserted" us, we should lookat what the Hadza people are eating. Our gut microbes depend on us as menu planners, and when our menu planning is bad, their growth is going to fail.
You,ve done a brilliant substack Jennifer I will keep this, thank you.
I eat only organic, keep some dirt/earth on it when cooking it. I’m a country type of person and a lot more healthy than a lot of people who spoil their bodies, microbiome , and their mind. I love nature, the rain, mud, I never wear shoes unless I have to, walk in country every day forest bathing, sometimes take the shoes off that I wore to drive there and walk bare foot even in the rain. I love gardening also, growing things watching the seasons change. Gods earth.
No sunglasses, I wear baseball cap, incandescent lights mostly, open windows, no chemicals in home (homemade stuff), no aerosol cans allowed, no TV now or for a great deal of my life can’t stand being anywhere with one.
Neem, zeolite, propolis toothpaste and mouthwash (mouth microbiome). No drugs, no alcohol.
I’m on the list for Dr Sabine Hazan’s list for microbiome control group.
Our internal "garden" menu planning is more dependent on the light signals, than the macromolecules. This is where team carnivore vs team plantbased fall down in the long-term.😉
Thought puzzle then,
From my menu planning perspective, I forgot to mention resistant starches as the other key food for butyrate species. I mentioned zinc.
The Carnivore diet is great for zinc but might be low in resistant starches.
The plant based diet might be lower in zinc and it might get bound up to plant chemicals. It would be good in resistant starch though. The gut microbes want quite a sizeable amount. Not a capsule supplement- macronutrient bulk.
Neither diet might have good butyrate producing species - given good lighting for both groups - in a hypothetical controlled experiment.
Interestingly, there were some issues with the Hadza studies design and data interpretation. But a big variable not accounted for is the light exposure. Microbial communities within the human body are also dependent on the sunlight via our belly being exposed at varying times during the day. Think chlorophyll in plants, likewise the microbes in our bodies synthesize all sorts of metabolites based on light signals.😉
Sunbathing or midriff tops in a new perspective 🤔
Jennifer I just looked and her name is Mary Ruddick on the video.
Dang, the title.... I had noticed that I had made a mistake, and double checked all the video mentions in the post and forgot to look at the title. thanks for mentioning it Solo.
I didn’t notice till now trying to search your substack and it didn’t come up, I went looking for books by her but couldn’t find any yet.
.
There is more videos on here.
MARY RUDDICK WEBSITE
Ancestral Nutritionist,
International Keynote Speaker,
Writer, & Film Scout
https://www.maryruddick.com/
Thanks Solo. She is good, I meant to look for more info from her too.
I fixed the title and added another section on resistant starch to the post.
.... and thoughts.