Includes chimeric spike gene sequences involved in fusion entry of cells, and Ehden Biber's latest post with FOIA information from Pfizer including the Omicron BA.1 ("Riltozinameran") genetic sequence
Influenza needs sialic acid (receptors) for binding or entry
therefore, changing or neutralizing the pH surrounding the cells might discourage binding or entry?
Inhalation of purified amorphous calcium sounds like a great plan if one can magically administer such a thing- but it might be like having a unicorn handy, not sure. It doesn't last long in its amorphous state and wants to become calcium carbonate crystals I believe.
The more sialic acid we have surrounding our cells (from eating red meat, possibly) the more inflammation we have thus, changing the pH/neutralizing the pH might hinder influenza.
It does sound familiar, doesn't it? Might be different though.
Cell entry (and cell signaling) is everything at the end of the day (whether mets from cancer or from infection). I have no idea what entry mechanisms influenza utilizes. I had hoped to not have to think about stuff like this so hard.. you know what I mean?
Sialic acid is what helps keep red blood cells from rouleaux stacking or intestinal wall from collapsing in on itself. I would need to dig a little more. If you look for 'mycoplasma' in my archives there should be a fairly recent post with extensive strategies. That can be part of the bad modern 'pneumonia' deaths.
https://www.mdpi.com/1999-4915/13/2/262 full text, lots of detail on different species sialic acid. I hesitate to think sialic acid is something to mess with. It is too important for lots of functions to recklessly inhibit it.
Cool. I got to meet him during my travels, he and his partner met me at a coffee shop with a box of books and I bought his newest one (2019) and a few others I didn't have. Very nice couple.
Regarding the evolution of chemicals, the Baccolini's theory of life section - there is a strong argument that DHA preceded genes and proteins based on the fact that it is still unchanged across species, yet nucleotides vary. Membranes are life and DHA is a quantum part of membranes. A document I wrote has references. https://docs.google.com/document/d/1TFYWh3OxMLJ0DcTJ3Hdn3tuGAzdN8BE6lV6jJg0ypkw/edit?usp=sharing
Noteworthy - "It has been known for at least 3 decades that L-ascorbic acid protects DNA from oxidative damage in human spermatocytes (Fraga et al. 1991)."
Ooooh "Ascorbolysis is postulated to provide the biophysical basis for the regio-, stereo-, and chemio-specificity of reversible post-translational modifications (PTMs) of proteins, including PTMs of genetic transcription factors, e.g. reversible PTMs of the NRF2-KEAP1 pathway (Mukhopadhyay 2015; Suzuki 2015; Song 2017)."
Jennifer, do you have ideas for avian flu?
Have you run across the Israeli amorphous calcium trials? (Covid)
Avian flu - the CoV preventative treatments should work, start early.
the calcium stuff sound interesting - I found a link about cancer use too. this is CoV - https://www.jpost.com/health-and-wellness/coronavirus/article-689543
Anti-cancer - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417113/
Influenza needs sialic acid (receptors) for binding or entry
therefore, changing or neutralizing the pH surrounding the cells might discourage binding or entry?
Inhalation of purified amorphous calcium sounds like a great plan if one can magically administer such a thing- but it might be like having a unicorn handy, not sure. It doesn't last long in its amorphous state and wants to become calcium carbonate crystals I believe.
The more sialic acid we have surrounding our cells (from eating red meat, possibly) the more inflammation we have thus, changing the pH/neutralizing the pH might hinder influenza.
It does sound familiar, doesn't it? Might be different though.
Cell entry (and cell signaling) is everything at the end of the day (whether mets from cancer or from infection). I have no idea what entry mechanisms influenza utilizes. I had hoped to not have to think about stuff like this so hard.. you know what I mean?
aaarrgghh
Pomegranate peel extract is our friend against dialysis c acid binding 😷 f flu virus https://www.dropbox.com/scl/fi/068694owbnm88k22ocaml/In-Vitro-Analysis-of-the-Anti-influenza-Virus-Activity-of-Pomegra.pdf?rlkey=ln2ealqq1iejknh04f10qpqcw&dl=0
*sialic
Sialic acid is what helps keep red blood cells from rouleaux stacking or intestinal wall from collapsing in on itself. I would need to dig a little more. If you look for 'mycoplasma' in my archives there should be a fairly recent post with extensive strategies. That can be part of the bad modern 'pneumonia' deaths.
https://www.mdpi.com/1999-4915/13/2/262 full text, lots of detail on different species sialic acid. I hesitate to think sialic acid is something to mess with. It is too important for lots of functions to recklessly inhibit it.
INTERESTING
Thank you for all of this!
Yeah! and you are very welcome!
Cool. I got to meet him during my travels, he and his partner met me at a coffee shop with a box of books and I bought his newest one (2019) and a few others I didn't have. Very nice couple.
Regarding the evolution of chemicals, the Baccolini's theory of life section - there is a strong argument that DHA preceded genes and proteins based on the fact that it is still unchanged across species, yet nucleotides vary. Membranes are life and DHA is a quantum part of membranes. A document I wrote has references. https://docs.google.com/document/d/1TFYWh3OxMLJ0DcTJ3Hdn3tuGAzdN8BE6lV6jJg0ypkw/edit?usp=sharing
Noteworthy - "It has been known for at least 3 decades that L-ascorbic acid protects DNA from oxidative damage in human spermatocytes (Fraga et al. 1991)."
Ooooh "Ascorbolysis is postulated to provide the biophysical basis for the regio-, stereo-, and chemio-specificity of reversible post-translational modifications (PTMs) of proteins, including PTMs of genetic transcription factors, e.g. reversible PTMs of the NRF2-KEAP1 pathway (Mukhopadhyay 2015; Suzuki 2015; Song 2017)."
https://ijvtpr.com/index.php/IJVTPR/article/view/12/14 PTM is something I got into in my Pom paper draft. I need to know more chemistry though.
Is "allosteric modulator" a similar concept to your ascorbolysis / NGTC?