B vitamins, selenium, cysteine also likely needed to prevent lymphedema. EGCG inhibits VEGF. Pomegranate may help lymphedema along with other sources of polyphenols inc: quercetin, rutin & myricetin.
great stuffs and thanks for sharing your supplement list!
i have added pomegranate fruit in my daily diet :) atleast 1 or two ..
what is your opinion on a combination of vinpocetine with ginkgo and piracitam? also recently i discovered that Niacin with Gaba and B1( at night) does wonderful job too! Niacin amuses me every other day with various combinations!!
I am glad to hear you are enjoying pomegranate and niacin/B1/GABA at night (that does sound like a helpful combination). Re vinpocetine with ginkgo and piracitam? No idea. Have you tried it?
not yet, days back was searching some combinations with piracitam and actually our chemist had that combination with vinpocetine and ginkgo with piracitam, so just bought that .. sometimes i take piracitam with nac+glycine with niacin (JP s combo),ginkgo i need to buy again....actually i want to try vinpocetine+ginkgo+piracitam with niacin :) but need to read more and then try! someone must have tried this combo too :)
AQP4 is aquaporin-4, it regulates the water and metabolite balance of glial cells & the spinal cord. Autoimmune antibodies can target it, which makes pomegranate of interest to avoid neuropathies.
And we can probably guess why "they" don't want flavonoids & polyphenols classed as vitamins. It would put half the pharma companies out of business in a few years;-)
"These results provide the first evidence suggesting that downregulation of NF-κB by Shp-1 alleviates CVST-induced brain edema through suppression of AQP4."
Baiqiang Chen, Xiangyi Kong, Zhuo Li, Wenjie Hu, Han Zhou, Jingchen Gao, Yu Cui, Shifang Li, Qi Wan, Yugong Feng, Downregulation of NF-κB by Shp-1 Alleviates Cerebral Venous Sinus Thrombosis-Induced Brain Edema Via Suppression of AQP4, Journal of Stroke and Cerebrovascular Diseases, 31(8,) 2022, 106570, ISSN 1052-3057, https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106570.
great stuffs and thanks for sharing your supplement list!
i have added pomegranate fruit in my daily diet :) atleast 1 or two ..
what is your opinion on a combination of vinpocetine with ginkgo and piracitam? also recently i discovered that Niacin with Gaba and B1( at night) does wonderful job too! Niacin amuses me every other day with various combinations!!
I am glad to hear you are enjoying pomegranate and niacin/B1/GABA at night (that does sound like a helpful combination). Re vinpocetine with ginkgo and piracitam? No idea. Have you tried it?
not yet, days back was searching some combinations with piracitam and actually our chemist had that combination with vinpocetine and ginkgo with piracitam, so just bought that .. sometimes i take piracitam with nac+glycine with niacin (JP s combo),ginkgo i need to buy again....actually i want to try vinpocetine+ginkgo+piracitam with niacin :) but need to read more and then try! someone must have tried this combo too :)
It all ends up in the same place - your stomach.
Good luck with your experimenting.
Wow, there's a lot in there to consider.
AQP4 is aquaporin-4, it regulates the water and metabolite balance of glial cells & the spinal cord. Autoimmune antibodies can target it, which makes pomegranate of interest to avoid neuropathies.
And we can probably guess why "they" don't want flavonoids & polyphenols classed as vitamins. It would put half the pharma companies out of business in a few years;-)
AQP4 is under circadian control. https://www.nature.com/articles/s41467-020-18115-2 That may be why I clear out at night but elevating my legs seems to help.
Let me sleep on it ;-)
You've just joined a dot for me:
Deletion of aquaporin-4 aggravates brain pathology after blocking of the meningeal lymphatic drainage
https://pubmed.ncbi.nlm.nih.gov/30347264/
Woot there it is - I am too inflamed.
"These results provide the first evidence suggesting that downregulation of NF-κB by Shp-1 alleviates CVST-induced brain edema through suppression of AQP4."
Baiqiang Chen, Xiangyi Kong, Zhuo Li, Wenjie Hu, Han Zhou, Jingchen Gao, Yu Cui, Shifang Li, Qi Wan, Yugong Feng, Downregulation of NF-κB by Shp-1 Alleviates Cerebral Venous Sinus Thrombosis-Induced Brain Edema Via Suppression of AQP4, Journal of Stroke and Cerebrovascular Diseases, 31(8,) 2022, 106570, ISSN 1052-3057, https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106570.
https://www.sciencedirect.com/science/article/pii/S1052305722002646
Yeah, I need to start over again in a document I think - on the lymphedema topic.. Read more and keep looking things up. I got tired.