Generationally, iodine deficiency has been accumulating and the current guidelines for pregnancy and lactation are likely too low. Low iodine and/or excess aluminum, may lead to breast cancer.
Interesting comment that hypothyroidism precedes breast ca. I have heard 3 MDs over the past yr mouth off some study that supplementing with iodine causes hypothyroidism.
No point in an argument. Requested a printed copy supporting their statement.
That type of statement is rattled off from schooling type of repetition. It is everywhere, the Wolff Chaikoff effect. It was a bad interpretation of a study that became the litany of current standards of care. Iodine used to be a treatment for many conditions and now it is barely used for the obvious ones that need it.
I started resveratrol many months ago and have slowly increased the dose to 500 mg per day. At first I bought the cheap stuff and then tried the more expensive stuff that comes in 500mg tabs.
Now I just found this article and now I don’t know what to think. 2mg/kg is an optimal dose? If so that sucks. Lol. I got less body aches with the higher dose.
Now what do I do? How much are other readers taking?
We don't absorb everything from a supplement and it can be hard to know what is meant be an experimental dose or how to convert from an animal study.
In the quote below, a 1000 mg daily dose was considered a high dose in a study with rats and it caused harm. You are larger and weigh more in Kg than lab rats. 500 mg for you would not be comparable to 1000 mg for a lab rat. The quote also mentions 20 mg/Kg causing no harmful effects.
Resveratrol is an estrogen receptor agonist so it has the power of a hormone - potent in tiny amounts.
Your link provided this paragraph: "Limited data exist regarding the adverse effects of resveratrol in aging. Juan et al. (2002) have shown that in rats, oral administration of 20 mg/kg resveratrol for 28 days produced no harmful effects as assessed by growth, hematology, clinical chemistry, and histopathology. In contrast, higher amounts of resveratrol (1000, and 3000 mg daily for 28 days) were shown to cause kidney damage (Crowell et al. 2004). Consumption of resveratrol at a modest dose results in an increase in the life span in case of 1 year old mice. However, when mice consumed larger doses (1800 mg/kg) of resveratrol, animals were shown to die within 3–4 months (Pearson et al. 2008)." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990065/
Interesting comment that hypothyroidism precedes breast ca. I have heard 3 MDs over the past yr mouth off some study that supplementing with iodine causes hypothyroidism.
No point in an argument. Requested a printed copy supporting their statement.
No paper proof yet.
That type of statement is rattled off from schooling type of repetition. It is everywhere, the Wolff Chaikoff effect. It was a bad interpretation of a study that became the litany of current standards of care. Iodine used to be a treatment for many conditions and now it is barely used for the obvious ones that need it.
Idiocracy is a cult classic. I encourage folks to view it. It is sooo relevant.
Great info as always. Thanks.
Off topic…..
I started resveratrol many months ago and have slowly increased the dose to 500 mg per day. At first I bought the cheap stuff and then tried the more expensive stuff that comes in 500mg tabs.
Now I just found this article and now I don’t know what to think. 2mg/kg is an optimal dose? If so that sucks. Lol. I got less body aches with the higher dose.
Now what do I do? How much are other readers taking?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990065/
We don't absorb everything from a supplement and it can be hard to know what is meant be an experimental dose or how to convert from an animal study.
In the quote below, a 1000 mg daily dose was considered a high dose in a study with rats and it caused harm. You are larger and weigh more in Kg than lab rats. 500 mg for you would not be comparable to 1000 mg for a lab rat. The quote also mentions 20 mg/Kg causing no harmful effects.
Resveratrol is an estrogen receptor agonist so it has the power of a hormone - potent in tiny amounts.
Your link provided this paragraph: "Limited data exist regarding the adverse effects of resveratrol in aging. Juan et al. (2002) have shown that in rats, oral administration of 20 mg/kg resveratrol for 28 days produced no harmful effects as assessed by growth, hematology, clinical chemistry, and histopathology. In contrast, higher amounts of resveratrol (1000, and 3000 mg daily for 28 days) were shown to cause kidney damage (Crowell et al. 2004). Consumption of resveratrol at a modest dose results in an increase in the life span in case of 1 year old mice. However, when mice consumed larger doses (1800 mg/kg) of resveratrol, animals were shown to die within 3–4 months (Pearson et al. 2008)." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990065/