Liked the info on Black eyed peas. I have microscopic colitin and I never have a problem with black eyed peas. No problem whatsoever. So go figure. Have a problem with almost every other beans.
Black eyed peas stand out from the rest of the beans in a few ways nutritionally. Good that you found them.
Microscopic colitin - had to look it up - colitis by another name.
Important things for colon microbiome health - eat enough zinc and resistant starch foods to feed the anaerobic butyrate producers that the colon needs. Using a butyrate product for a month while trying to get that established might help too, because if the colon cells are using aerobic glycolysis to produce their energy, then the colon won't be anaerobic and it needs to be for optimal function.
My gut feels better when I get some tapioca or arrowroot starch in something. Vietnamese salad roll wraps are tapioca starch.
Neat, I haven't tried lupini beans NN. It was new to me. Controversial take on Twitter - "It is hard to get enough protein on a vegan diet." Then I got several replies about it is easy to do. It made me realize - I am on an autoimmune diet, with more restrictions than vegan.
my buddy Brave AI (favism is a bean toxin problem):
The glucose-6-phosphate dehydrogenase (G6PD) enzyme plays a crucial role in the pentose phosphate pathway, which is essential for the production of NADPH and pentoses. Deficiencies in G6PD have been linked to various clinical manifestations, including favism, hemolytic anemia, and increased susceptibility to infections.
Legume Digestion
Legumes, such as beans, lentils, and peas, are rich in complex carbohydrates, proteins, and fiber, making them a nutritious and versatile food source. However, their digestion is complex and influenced by various factors, including the structure and composition of the legume cell wall, the presence of anti-nutritional factors, and the activity of digestive enzymes.
Interaction between G6PD and Legume Digestion
Recent studies have investigated the interaction between G6PD and legume digestion. One study found that the G6PD enzyme is involved in the degradation of legume cell walls, which is essential for the release of nutrients. The study used a laboratory model that mimics the mechanical and biochemical conditions of the rat stomach and duodenum and found that intact legume cells were resistant to enzymatic digestion, but when broken, the hydrolysis of starch and protein was increased.
Another study investigated the effect of G6PD deficiency on legume digestion and found that individuals with G6PD deficiency had impaired digestion of legumes, which was attributed to the reduced activity of the G6PD enzyme. The study suggested that the preservation of intact legume cells could be a viable approach to achieve the targeted delivery of resistant starch to the colon.
Conclusion
In conclusion, the G6PD enzyme plays a crucial role in the digestion of legumes, and deficiencies in G6PD can impair the digestion and absorption of nutrients from legumes. Further research is needed to fully understand the interaction between G6PD and legume digestion and to develop strategies to improve the nutritional value of legumes for individuals with G6PD deficiency.
Context
- Digestion of isolated legume cells in a stomach-duodenum model: three mechanisms limit starch and protein hydrolysis - PubMed https://pubmed.ncbi.nlm.nih.gov/28682366/
- A trade off between catalytic activity and protein stability determines the clinical manifestations of glucose-6-phosphate dehydrogenase (G6PD) deficiency - PMC, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625996/
- Detailed functional analysis of two clinical glucose-6-phosphate dehydrogenase (G6PD) variants, G6PDViangchan and G6PDViangchan+Mahidol: Decreased stability and catalytic efficiency contribute to the clinical phenotype. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894296/
Yes G6PD deficiency!!!!! I am not in a typical group that has it. I get subclinical haemolysis if I ingest any leading to fatigue and brain fog. I was 63 when I found it and it had been a contributing factor to CFS over the years.
Liked the info on Black eyed peas. I have microscopic colitin and I never have a problem with black eyed peas. No problem whatsoever. So go figure. Have a problem with almost every other beans.
Black eyed peas stand out from the rest of the beans in a few ways nutritionally. Good that you found them.
Microscopic colitin - had to look it up - colitis by another name.
Important things for colon microbiome health - eat enough zinc and resistant starch foods to feed the anaerobic butyrate producers that the colon needs. Using a butyrate product for a month while trying to get that established might help too, because if the colon cells are using aerobic glycolysis to produce their energy, then the colon won't be anaerobic and it needs to be for optimal function.
My gut feels better when I get some tapioca or arrowroot starch in something. Vietnamese salad roll wraps are tapioca starch.
JD - Excellent work on lectins. I do love me some lupini beans, pop em out of the skin and chase with a beer.
Neat, I haven't tried lupini beans NN. It was new to me. Controversial take on Twitter - "It is hard to get enough protein on a vegan diet." Then I got several replies about it is easy to do. It made me realize - I am on an autoimmune diet, with more restrictions than vegan.
Unless you have G6PD - then you cannot eat any legumes.
Don't have G6PD you mean? that is interesting.
my buddy Brave AI (favism is a bean toxin problem):
The glucose-6-phosphate dehydrogenase (G6PD) enzyme plays a crucial role in the pentose phosphate pathway, which is essential for the production of NADPH and pentoses. Deficiencies in G6PD have been linked to various clinical manifestations, including favism, hemolytic anemia, and increased susceptibility to infections.
Legume Digestion
Legumes, such as beans, lentils, and peas, are rich in complex carbohydrates, proteins, and fiber, making them a nutritious and versatile food source. However, their digestion is complex and influenced by various factors, including the structure and composition of the legume cell wall, the presence of anti-nutritional factors, and the activity of digestive enzymes.
Interaction between G6PD and Legume Digestion
Recent studies have investigated the interaction between G6PD and legume digestion. One study found that the G6PD enzyme is involved in the degradation of legume cell walls, which is essential for the release of nutrients. The study used a laboratory model that mimics the mechanical and biochemical conditions of the rat stomach and duodenum and found that intact legume cells were resistant to enzymatic digestion, but when broken, the hydrolysis of starch and protein was increased.
Another study investigated the effect of G6PD deficiency on legume digestion and found that individuals with G6PD deficiency had impaired digestion of legumes, which was attributed to the reduced activity of the G6PD enzyme. The study suggested that the preservation of intact legume cells could be a viable approach to achieve the targeted delivery of resistant starch to the colon.
Conclusion
In conclusion, the G6PD enzyme plays a crucial role in the digestion of legumes, and deficiencies in G6PD can impair the digestion and absorption of nutrients from legumes. Further research is needed to fully understand the interaction between G6PD and legume digestion and to develop strategies to improve the nutritional value of legumes for individuals with G6PD deficiency.
Context
- Digestion of isolated legume cells in a stomach-duodenum model: three mechanisms limit starch and protein hydrolysis - PubMed https://pubmed.ncbi.nlm.nih.gov/28682366/
- A trade off between catalytic activity and protein stability determines the clinical manifestations of glucose-6-phosphate dehydrogenase (G6PD) deficiency - PMC, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625996/
- Detailed functional analysis of two clinical glucose-6-phosphate dehydrogenase (G6PD) variants, G6PDViangchan and G6PDViangchan+Mahidol: Decreased stability and catalytic efficiency contribute to the clinical phenotype. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894296/
Yes G6PD deficiency!!!!! I am not in a typical group that has it. I get subclinical haemolysis if I ingest any leading to fatigue and brain fog. I was 63 when I found it and it had been a contributing factor to CFS over the years.
Cheers.