Galectin-3 inhibition for CoV is in the news - Epoch Times News
Modified citrus pectin, pomegranate inner pith, rhubarb, and apples are sources of pectin with is an inhibitor. So is milk sugar - lactose.
Modified citrus pectin is being considered for use but clinical trials to prove efficacy are still needed. (Also needed for pomegranate peel/inner pith has pectin too.)
Galectin-3 and the key to relieving Covid-19 symptoms. (theepochtimes.com)
The use of modified citrus pectin as a galectin-3 inhibitor for LongCovid patients is discussed in a video by Evan H. Hirsch, MD with Isaac Eliaz, MD.
Dr. Eliaz discusses galectin-3 and modified citrus pectin as a treatment in a video a few years ago: Galectin-3: A New Target For Inflammation with Dr Isaac Eliaz (Youtube)
Elevated galectin-3 is inflammatory and elevated levels may play a role in liver, kidney or heart disease. It is also used for cancer treatment. Citrus bioflavonoids and pectin is also used for weight control and Metabolic Syndrome.
Pectin and milk sugar, lactose, helps inhibit galectin-3 effects. Addition, a reply shared more galectin-3 inhibitors found in plant foods:
DoorlessCarp🐭, Writes DoorlessCarp’s Scientific Liter…, 4 mins ago,
“I'm glad you've posted this Jen. Gal-3 is particularly nasty, its involved with almost every disease and disorder at some level.
Other inhibitors including Fenugreek, Quercetin, Resveratrol, Berberine, aspirin, Nigella sativa seed (black seed) & silymarin:
Modified citrus pectin has the long chain of fibrous starch shortened somewhat which seems to help efficacy for improving blood lipids and blocking galectin-3 effects. A secondary benefit of modified citrus pectin also can bind with heavy metals which helps for removing them from the body. Memory, joint pain and energy level can improve with use of modified citrus pectin per Dr. Eliaz.
Product example - PectaSol-C R Professional Lime - Clinical Synergy Professional
"PectaSol-C® Professional is a natural inhibitor of galectin-3 (Gal-3), a protein involved in cardiovascular health.* Research shows that modifying Gal-3 levels in the circulation supports healthy aging, cellular function, cardiovascular health and normal immune response.* PectaSol-C® Professional is a low molecular weight pectin from the pith of citrus fruit peels, increasing absorption to provide benefits systemically.* PectaSol-C® Professional Modified Citrus Pectin is supported by over 20 published peer-reviewed studies and over 20 years of research."
$54.99 for 18 grams, take one scoop a day is the directions (6.125g), ( - 5g Modified Citrus Pectin).
I added this product in a brief Fullscript protocol/plan - enroll as a client of mine for a 20% discount. (Fullscript/Pectin & Galectin-3)
Citrus fruit is less expensive and the inner pith is mildly sweet to simply eat. Five grams dehydrated powder would be about a teaspoon or so of fresh inner pith. The outer zest is not as good a source of pectin and is very potent in other phytonutrients.
A related post has a lot of detail:
VEGF, galectin-3, chimeric spike, and milk sugar. Oct. 1, 2022. (Substack)
The Too Long; Didn’t Read on that post is fairly lengthy but helps fill in the details:
The Too Long; Didn’t Read version of VEGF, galectin-3, chimeric spike, and milk sugar.
The fiber content of the inner pith includes pectin which adds to the synergistic value as an inhibitor of galectin-3. Rhubarb pectin and other plant pectin are effective galectin-3 inhibitors and beneficial for fibrotic cardiovascular conditions. (Pozder Geb Gehlken, et al, 2021) The spike subunit S-1 has a similar sequence to galectin-3 which may be promoting angiogenesis. (Schroeder and Bieneman, 2022) Galectin-3 promotes angiogenesis by affecting the vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) control of angiogenesis. (Mehta and Granstein, 2019). Beta-lactose (milk sugar) and dominant-negative galectin-3 are also inhibitors. (Markowska, et al, 1981)
VEGF and its receptors are increased in myocarditis. (Li J, et al, 1996) Galectin-3 has a high predictive value as a marker for increased risk of re-hospitalization and mortality in heart failure patients. Change in level or maintenance also had predictive value and appeared in a dose related manner – a larger increase had a worse risk compared to smaller increase and a decrease was protective compared to maintaining an elevated level. (Chen et al., 2015, cited by Amin et al, 2017) Inhibiting Galectin-3 with GB1107 led to reduced IL-1, IL-6 and TNF-α levels in a spinal cord injury model. (Ren et al., 2019, cited by Caniglia, et al, 2020) Abnormal expression of galectins is seen in liver damage (Yang A, et al, 2021) and galectin-3 excess is associated with fibrotic kidney damage, while it is anti-inflammatory for an acute risk. (Chen and Kuo, 2016)
Galectin-3 has regulatory effects on apoptosis and disruption might lead to senescent cells. (Seyrek, et al, 2019) Senescent cells are a greater risk for elderly patients and quercetin and fisetin are two phytonutrients with anti-senolytic benefits. (Lynch, et al, 2021) Pomegranate peel has quercetin content. (Gullón, et al, 2020, Fig. 1)
Zinc also gets a mention, and α-Melanocyte-stimulating hormone (α-MSH), Beta-ionine and a good suntan.
More about α-MSH and weight control is included in the next post:
α-MSH, regulator of appetite and weight and our bone matrix. (& we need Zinc too!) (substack.com)
and Rhubarb is featured in the next one: Rhubarb deserves more than one line. (substack.com).
Ice cream as a healthy food? Researchers wanted to bury these findings. Let’s look for a mechanism of action instead. June 17, 2023 (Substack)
Pectin is also in the inner pith of pomegranate peel. Rhubarb stalk and Turkey rhubarb root pectin are also a beneficial health foods.
Pomegranate peel phytonutrients help fight chimeric spike in a large number of ways, but spike has even more ways to harm. Beta-glucan in mushrooms and Nutritional yeast flakes, oatmeal and barley is also protective of dectin-1 receptor function which is to protect against yeast infections.
There are more than four major ways that spike effects long term health risks. I count 13 currently. There are also solutions - more than 13. Feb. 3,202, (Substack)
There are more than four major ways that spike effects long term health risks. I count 13 currently. There are also solutions - more than 13.
Four major ways the spike effects health risk per Adam Gaertner’s post: The Truth About Vax Detox - by Adam Gaertner - veryvirology (substack.com). It is behind a paywall and seems quite negative in outlook besides blithly stating only four major problems and suggests lap dances? I must admit to being tired of paywalls and spending money on paywalls on …
Disclaimer: This information is being provided for educational purposes within the guidelines of Fair Use and is not intended to provide individual health care guidance.
$54.99 for 18 grams, take one scoop a day is the directions (6.125g)
that sounds like an expensive habit
i make a smoothie out of a lemon (seeds removed coz they turn into toenail clippings ha) some apple cider vinegar and some ginger root! It's surprisingly smooth, without the sourness of squeezed lemon.
I don't have long anything... i just like it and surely it's gotta be good for me😁