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The brain is made of significant amounts of cholesterol and statins, I seem to recall, are associated with dementia for this reason.

https://jnm.snmjournals.org/content/62/supplement_1/102

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Jennifer, your research and how you described cholesterol as a calcium cap with electrical destructive power coincides with my research of how calcium efflux is increased with emf: https://romanshapoval.substack.com/p/how-flu-is-an-electrical-illness

Don't statins also lower testosterone, and by that factor human growth hormone, which would also not help neurodegeneration?

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Yes, testosterone is reduced.

Thanks for the link, will look later.

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Thanks Jennifer. No pressure, it's a looooong article (:

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That was really well done, thanks for sharing the link.

Magnesium adequacy in advance would be protective - help stop the calcium flow in response to the electrical stimuli - if not too strong. Problem is the strength keeps being increased.

See https://denutrients.substack.com/p/emfs-and-intracellular-calcium-magnesium-is-natures-calcium-channel-blocker, Dec. 21, 2017

Polyphenols, niacin and butyrate would also be protective and extra B's, C, etc, more mitochondrial support as those nutrients get used up excessively under stress of any sort.

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Thank you Jennifer. Do have a favorite form of magnesium? Currently I'm taking bisglycinate, l-threonate, and magnesium oxide.

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That is a good combo. I personally really seem to need the topical Epsom salt or symptoms return. Muscle cramps, cranky, and teary.

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Good to know- thanks for sharing this Jennifer.

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I lost the statin argument not having any medical standing. I'm helping care for a family member with alzheimers and their neurologist took her off one of the statins and months later we got a message from a lab tech demanding to know why she was taken off the statin.

I brought as much research and studies as the primary care giver/guardian would tolerate in a twenty minute reading session. They seemed unconvinced and ready to be spoonfed whatever pharmacaptured crap a lab tech or bought doc will tell them. It's frustrating but I really do not have any medical standing and can only differ to a system that I no longer trust.

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Sorry to hear you are having to tackle the system.

Of you could give her extra D3 or egg yolk foods that would give her some more cholesterol.

The system is frustrating.

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Mar 11, 2023Liked by Jennifer Depew, R.D.

Long story short I stopped my statin a few weeks ago.

Now what should I do? How much magnesium should I take a day? Right now I’m taking 375 mg of mixed OTC magnesium. I have always wondered if I should take more.

Any other recommendations that I could be missing?

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That would be enough if there is normal kidney function and okay GI absorption. I have found topical Epsom salt soaks are a need for me even with lots of magnesium in my diet.

I would suggest just trying it and seeing if it makes a difference in symptoms - do you feel better after topical magnesium? or about the same? If it doesn't make a difference then you are getting enough in the diet.

Plenty of water is also important for vascular health and enough potassium. I try to have a big salad every day rather than too much fruit.

Otherwise I am not sure what your issues are. Were you on statins just as a precaution?

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Mar 12, 2023·edited Mar 12, 2023Liked by Jennifer Depew, R.D.

Hi. Thanks for your reply.

I was put on 20 mg Lipitor years ago and reduced and switched to rosuvastatin 10 mg soon after due to muscle aches.

Apparently my cholesterol was high.

After the vax I was “ brain drunk” for 2 months and now have chronic brain fog with terrible memory issues. My doctor now thinks I have fibromyalgia. I started getting migraines with aura with no headache. Lol. I can’t see well sometimes. It comes and goes.

I read about the possible memory issues with statins. So since I changed my diet and use Metamucil/fiber to help rid excess cholesterol I stopped my statin.

Not sure if it’s a good idea. Lol.

Ps Just letting you know just in case that google is frequently sending your emails and comments to my junk box!!! Maybe other people are affected too?

Edit. I failed to mention....

I read Pu-erh tea might help with cholesterol too. Not sure if true but I take it after my normal supper that I eat with Metamucil. Lol.

So I will get tested in the future to see where I am with my cholesterol level.

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I have noticed big name CoV writers on Substack show up in my junk mail too.

I guess I should feel complimented. 😕

Re fibromyalgia like symptoms following CoV era, I would strongly encourage you to just try eliminating vitamin A and carotenoid rich foods for a couple weeks and see if symptoms reduce. A gene change may have occurred that causes longterm overactivation of Retinoic Acid which is inflammatory.

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Mar 13, 2023Liked by Jennifer Depew, R.D.

Thanks.

I’ll try that then. I read an article where you mentioned it.

Take care superstar

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Thanks 🙏 😊

You too!

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Mar 11, 2023Liked by Jennifer Depew, R.D.

Would the use of a water soluble stain instead of a fat soluble statin help reduce the dementia in the brain?

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Polyphenols help like apples with the peel, pomegranate fruit or peel extract, hawthorne, others.

I don't think there is a water soluble statin vs a fat soluble one.

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Mar 10, 2023·edited Mar 10, 2023

"The prevalence of moderate to severe brain atherosclerosis was 54% among 1905-1914 births, 37% for 1915-1919, 30% for 1920-1924, and 22% for 1925-1930, while moderate/severe arteriolosclerosis ranged from 44% for those born from 1905-1914 to 28% from 1925-1930 (χ2 test: P<0.001 across birth year categories). However, there were no differences in age-standardized prevalence of gross chronic infarcts over time, and microinfarcts were more prevalent with later year of birth."

There are SO many variables here, and in these time frames, that I think it irresponsible journalism to lay it at the feet of one (statins) on the basis of sheer speculation. There is not even a speck of data cited for statin use in these populations, or comparators to non-dementia populations.

Also, why more micro-infarcts? Particularly in an era with MORE aggressive treatment of hypertension?

There is still much to understand about tau protein, amyloid, and dementias.

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Mar 11, 2023·edited Mar 11, 2023Author

I significantly expanded the post to address your point somewhat. My time is limited and I still need to read the dementia autopsy study rather than the MedPage article.

I have spent a lot of time on this topic and would arm wrestle with you on it.

Addition - and "a confounding variable" inherently suggests that there are other confounding variables too. I was not suggesting statins exclusively were causal - it seems irresponsible to not mention that 48% of adults over age 75 take or have taken statin meds though, in a discussion of reduced atherosclerosis or arteriosclerosis.

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Please understand when I mentioned irresponsible journalism, I did not mean you! I meant the MedPage Today author.

Arm-wrestling unnecessary.

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