11 Comments
Sep 25Liked by Jennifer Depew, R.D.

Dopamine is waaaaaaaay more than just a neurotransmitter.πŸ˜‰

But side note, very interesting when you have a look at the "hypersexualisation" as an effect of dopamine receptors, in mild Parkinson's.πŸ€” then consider a society that is avoiding sunshine, receiving incorrect signalling via excessive blue light (devices), and the synergistic impacts from vitD which is involved in regulating dopamine.πŸ€”πŸ˜πŸ€¨

We are light beings. It influences EVERYTHING in, on and around us.

If your not addressing it, your only dealing with a fraction of the problem.

Kruse is annoying but accurate in lots of areasπŸ˜‰πŸŽ―

Keep following the light, especially for you Jennifer. πŸ€— but also focus on how it affects your vagal nerve.πŸ˜‰

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Thanks! I guess I should look into dopamine a bit more. It is really complex in PD.

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Sep 26Β·edited Sep 26Liked by Jennifer Depew, R.D.

Oh that was an intriguing comment ! Can you give me a hint about what else dopamine is up to? Or where to look?

acting as a hormone.? is that what you meant? thanks!

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Sep 26Β·edited Sep 26Author

Dopamine's reward-like value is used against us by nudging us towards desired goals or by instilling fear or excitement in order to leave people more gullible to suggestion or following commands.

Let's see what Brave AI can summarize for us "what roles does dopamine have besides neurotransmitter functions?":

Dopamine Roles Beyond Neurotransmission

Based on the provided search results, dopamine has several roles beyond its neurotransmitter functions:

Regulation of gene expression: Dopamine plays a role in regulating gene expression, particularly in response to reward and stress. This is evident from the mention of dopamine’s involvement in β€œneurotransmitter reuptake” and its regulation by oxidative stress (Search Result 1).

Influence on immune system: Dopamine has been linked to the immune system, as seen in the mention of dopamine’s interaction with microglia, a type of immune cell, in the context of psychiatry (Search Result 1).

Role in neurocognitive function: Dopamine is involved in the neurocognitive function of the frontal lobe, controlling the flow of information from the brain (Search Result 1).

Modulation of oxidative stress: Dopamine’s dysfunction is implicated in oxidative stress, which contributes to various nervous system diseases (Search Result 1).

Influence on gut-brain axis: Dopamine is mentioned alongside serotonin in its role in digestion and sleep, suggesting a connection to the gut-brain axis (Search Result 5).

Regulation of movement and motor control: Dopamine’s dysfunction is linked to Parkinson’s disease, a condition characterized by impaired motor control (Search Result 1).

Involvement in addiction: Dopamine’s role in reward processing and motivation is implicated in addiction, as seen in the mention of dopamine’s interaction with other neurotransmitters and hormones (Search Result 4).

Regulation of mood and emotions: Dopamine’s imbalance is associated with mental health conditions such as schizophrenia and depression, highlighting its role in mood regulation (Search Result 5).

These roles demonstrate dopamine’s broader impact beyond its classical neurotransmitter functions, influencing various physiological and psychological processes.

https://search.brave.com/search?q=what+roles+does+dopamine+have+besides+neurotransmitter+functions%3F&source=desktop&summary=1&summary_og=d065056fbc65c3780fedc3

Gut-brain axis and vagal nerve activity might be worth a closer look - Barefoot Healer has encouraged me to work on my vagal health.

JuΓ‘rez OlguΓ­n H, CalderΓ³n GuzmΓ‘n D, HernΓ‘ndez GarcΓ­a E, BarragΓ‘n MejΓ­a G. The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress. Oxid Med Cell Longev. 2016;2016:9730467. doi: 10.1155/2016/9730467. Epub 2015 Dec 6. PMID: 26770661; PMCID: PMC4684895. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684895/

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Oct 1Liked by Jennifer Depew, R.D.

Partly, but saying dopamine is a neurotransmitter is like saying an Apple Iphone is a clock. It HAS a clock function, but is that its primary use/ability?πŸ€”πŸ€¨

My comment was from the aspect that dopamine is created in response to internal/external signals. So if we look at "Parkinsons" as a symptom, rather than a disease , then that changes the question quite a bit.

My comment that the current hyper-sexualisation of society as a whole, would be a very interesting concept to look at, as a symptom of circadian disruption and full spectrum deficiency relating to the dysregulation of dopamine in the brain, especially when you add in the effects of device usage (unscheduled blue light).πŸ˜‰

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Gotcha.

Blue light of differing wavelengths can either cause or inhibit degranulation of mast cells in the skin and an excess of histamine can cause hypersexuality.

https://research.tue.nl/en/publications/human-skin-mast-cells-express-photoreceptors-and-blue-light-inhib

https://pubmed.ncbi.nlm.nih.gov/37442837/

It seems that more light exposure also leads to an increase in number of mast cells. These studies are looking at use of light for wound healing. https://www.sciencedirect.com/science/article/abs/pii/S1011134410000023

Red light therapy stabilizes mast cells. https://drtaniadempsey.com/red-light-therapy-for-mcas-could-it-be-a-promising-approach/

Flickering, strobe lights, action movies, car headlights at night from oncoming traffic, all left me with migraines a few hours later. I learned to wear dark sunglasses. The flickering light triggers mast cell degranulation I learned. Link on my Histamine/MCAS page on jenniferdepew.com

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Or is the flickering a response to mast cell degranualation, which is a compensation reaction to deregulated light?πŸ€” Reframe the solution, to find the question we need to be asking. Jack's good but he's not the be all, and should not be the sole source of information on photonics. Sunglasses are bandaid not solution in the long run but you know that πŸ˜‰ be well.

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Strobe lights trigger degranulation. Leads to excess histamine later if you lack the enzyme or methyl groups to deactivate it. I tend to do my own PubMed digging. Kruse has paywalls (and not enough summaries).

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Bernice Eddy, I haven't heard her name in a while, her story needs to be told more.

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Definitely!!πŸ’―πŸ“£πŸ“£πŸ“£πŸ‘πŸ˜‰

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πŸ’‘Have become an incandecent light bulb collector, lol.

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