JD - "there wasn’t a lot of evidence-based research regarding health benefits of drinking structured water instead of tap water". There's a boat load of varied studies, just use "deuterium depletion". Funny thing is, you run into a wall of trees all about DDW and nothing else. Then you start cross referencing the papers and authors, all the bread crumbs lead in circles. Then you try and find another way aside from diet and water to "deplete deuterium", and you can't find one through all those trees. Then you see the forest for the trees, and realize, this is all about creating a narrative to sell absurdly priced "filtered" water. If it walks, smells and looks like one, it is.
Yes, big market to sell stuff. The water course had a long list of references but I have to click each one and recreate a reference list because his isn't copy/paste-able or downloadable.
There is research but the "double blind human clinical trial" "evidence-based research" isn't done on stuff like this unless, maybe, to sell a product. I need to look into more realistically. Accurate writing would say "I am not aware of double blind.... etc."
things can be made to be simple and fast - remembering to do the simple fast thing is also an issue and that is where practice and trying can help while thinking stuck thoughts "I can't so I won't try" is not going to get anywhere else. So why not try? because, ... but baby steps helps me get unstuck sometimes.
Dr Smith is the owner of the twitter account and the website. He has tweeked the detox procedure from information he garnered from Grant Genereux. Grant has 3 free e-books on vitamin A toxicity.
Thanks. I will look into it as that is a research focus of mine too. My night vision is fine with limited carotenoids and vitamin A too. It is fairly difficult to restrict enough. I really have to limit my deep green veggies, not just carrots and obvious carotenoid foods.
Jennifer, you were the first to person that mentioned the problems with vitamin A and this lead me to Dr Smith and Grant. https://ggenereux.blog/.
Talk about a liver detox-whew!
I feel a teeny bit better every day, been at it a month. Been suffering from gallbladder pain for 4 years, not a twinge in two weeks now. Fingers crossed.
Really interesting link. Yes, it took me a while for symptoms to fully improve but I must have done better than that person at restricting some things early in my life that were inflammatory for me like dairy products. Interesting that casein binds vitamin A. I will have to look at that link closer later.
Thanks Jennifer, for this extremely well-articulated and informative article. The Cheerful Juice/Dimethylglycine drink recipe is enticing. I am agog to try it! Thanks again for sharing this wealth of information. A riveting read indeed!
Thanks! I should do more with it. Salicylate sensitivity articles online don't provide the glycine info typically. Instead the tendency is to just talk about food restrictions without suggesting improvement is possible if you lower your internal acidity and increase use of glycine. I need the DMG type genetically but maybe the TMG (betaine) would help some people too. Methylation gene difference products always include the betaine type but that wouldn't help with my gene differences
Yes, Methylation gene difference products, such as supplements or dietary sources, often include betaine --but as I understand, it can help with gene differences by supporting the methylation process.
Betaine supplementation has been shown to increase the levels of S-adenosylmethionine/ SAM, which can improve the methylation status of DNA & other molecules in the body.
This can help regulate gene expression and cellular processes that may be affected by methylation gene differences.
However, it's important that the effectiveness of betaine supplementation may vary depending on the specific methylation gene differences and individual factors...
That was my point - one of my gene alleles makes it harder for me to convert betaine to DMG - so more betaine can make me worse. I specifically need the DMG because my enzyme to breakdown betaine doesn't work right.
Any standard 'methylation' mixed supplement product wouldn't be good for me was my point, I NEED the DMG not betaine/TMG.
Agree with you...while standard 'methylation' mixed supplement products can be helpful for many people, some individuals may need to use DMG instead of betaine or TMG due to genetic variations, specific health conditions, individual differences in metabolism, or specific nutrient requirements...
Agreed. Given the complexity of methylation support and the potential impact of genetic differences, it is essential for individuals to be aware of their unique genetic makeup and work with healthcare professionals to develop personalized strategies for optimizing their methylation processes.
This may involve dietary modifications, supplementation, and lifestyle changes tailored to an individual's specific genetic profile...
JD - "there wasn’t a lot of evidence-based research regarding health benefits of drinking structured water instead of tap water". There's a boat load of varied studies, just use "deuterium depletion". Funny thing is, you run into a wall of trees all about DDW and nothing else. Then you start cross referencing the papers and authors, all the bread crumbs lead in circles. Then you try and find another way aside from diet and water to "deplete deuterium", and you can't find one through all those trees. Then you see the forest for the trees, and realize, this is all about creating a narrative to sell absurdly priced "filtered" water. If it walks, smells and looks like one, it is.
Yes, big market to sell stuff. The water course had a long list of references but I have to click each one and recreate a reference list because his isn't copy/paste-able or downloadable.
There is research but the "double blind human clinical trial" "evidence-based research" isn't done on stuff like this unless, maybe, to sell a product. I need to look into more realistically. Accurate writing would say "I am not aware of double blind.... etc."
JD this is a fantastic article.
I'm posting this and then deleting most of it, because it is just for you to see. So you can see it in your inbox.
Did you see this post? https://open.substack.com/pub/denutrients/p/bath-time-and-journaling-for-habit?r=os7nw&utm_campaign=post&utm_medium=web
things can be made to be simple and fast - remembering to do the simple fast thing is also an issue and that is where practice and trying can help while thinking stuck thoughts "I can't so I won't try" is not going to get anywhere else. So why not try? because, ... but baby steps helps me get unstuck sometimes.
You starting a virtual clinic is a fantastic idea. 👍
Thanks!
Dr Smith is the owner of the twitter account and the website. He has tweeked the detox procedure from information he garnered from Grant Genereux. Grant has 3 free e-books on vitamin A toxicity.
Thanks. I will look into it as that is a research focus of mine too. My night vision is fine with limited carotenoids and vitamin A too. It is fairly difficult to restrict enough. I really have to limit my deep green veggies, not just carrots and obvious carotenoid foods.
https://nutritiondetective.com/
@nutridetect on X
Jennifer, you were the first to person that mentioned the problems with vitamin A and this lead me to Dr Smith and Grant. https://ggenereux.blog/.
Talk about a liver detox-whew!
I feel a teeny bit better every day, been at it a month. Been suffering from gallbladder pain for 4 years, not a twinge in two weeks now. Fingers crossed.
Is Nutrition Detective your site and Twitter handle or you are sharing a resource with me? If so, it does look like my kind of group.
Really interesting link. Yes, it took me a while for symptoms to fully improve but I must have done better than that person at restricting some things early in my life that were inflammatory for me like dairy products. Interesting that casein binds vitamin A. I will have to look at that link closer later.
https://timothywiney.substack.com/p/chia-seeds-in-95-ph-mineral-water
Thanks Jennifer, for this extremely well-articulated and informative article. The Cheerful Juice/Dimethylglycine drink recipe is enticing. I am agog to try it! Thanks again for sharing this wealth of information. A riveting read indeed!
Thanks! I should do more with it. Salicylate sensitivity articles online don't provide the glycine info typically. Instead the tendency is to just talk about food restrictions without suggesting improvement is possible if you lower your internal acidity and increase use of glycine. I need the DMG type genetically but maybe the TMG (betaine) would help some people too. Methylation gene difference products always include the betaine type but that wouldn't help with my gene differences
Yes, Methylation gene difference products, such as supplements or dietary sources, often include betaine --but as I understand, it can help with gene differences by supporting the methylation process.
Betaine supplementation has been shown to increase the levels of S-adenosylmethionine/ SAM, which can improve the methylation status of DNA & other molecules in the body.
This can help regulate gene expression and cellular processes that may be affected by methylation gene differences.
However, it's important that the effectiveness of betaine supplementation may vary depending on the specific methylation gene differences and individual factors...
That was my point - one of my gene alleles makes it harder for me to convert betaine to DMG - so more betaine can make me worse. I specifically need the DMG because my enzyme to breakdown betaine doesn't work right.
Any standard 'methylation' mixed supplement product wouldn't be good for me was my point, I NEED the DMG not betaine/TMG.
Agree with you...while standard 'methylation' mixed supplement products can be helpful for many people, some individuals may need to use DMG instead of betaine or TMG due to genetic variations, specific health conditions, individual differences in metabolism, or specific nutrient requirements...
Other people may need to riboflavin or thiamin due to a blockage leading to excess folate. Then a folate supplement would make them worse.
Methylation support is complex, or it can be when genetic differences are unknown.
Agreed. Given the complexity of methylation support and the potential impact of genetic differences, it is essential for individuals to be aware of their unique genetic makeup and work with healthcare professionals to develop personalized strategies for optimizing their methylation processes.
This may involve dietary modifications, supplementation, and lifestyle changes tailored to an individual's specific genetic profile...