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DrSDRK's avatar

Thanks for the well articulated and informative article. Proton pump inhibitors (PPIs)-- medications commonly used to treat acid reflux, gastroesophageal reflux disease (GERD), and peptic ulcers reduce the production of stomach acid, I agree with you.

Recent research has shown that long-term use of PPIs may be linked to the worsening of liver disease.

The liver plays a crucial role in the body's metabolic processes, including the breakdown of nutrients, the production of bile, and the detoxification of harmful substances.

It is also involved in the regulation of blood clotting and the removal of bacteria from the bloodstream.

There are several ways in which PPIs may contribute to the worsening of liver disease:

Alteration of the gut microbiome: PPIs can change the balance of bacteria in the gut, leading to an overgrowth of harmful bacteria that can produce toxins and cause inflammation in the liver.

Impaired nutrient absorption: PPIs can reduce the absorption of important nutrients like vitamin B12 and magnesium, which are essential for liver health.

Increased risk of infections: PPIs can increase the risk of infections like Clostridium difficile, which can cause inflammation and damage to the liver.

Reduced liver function: PPIs can decrease the production of bile, which is important for the digestion of fats and the removal of toxins from the liver.

Your article is very telling, deep in depth and spot on. Thanks Jennifer. Keep your articles coming. Very informative indeed.

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Dr Maria D Olivier🇿🇦's avatar

Thank you

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