Bifidobacterium, CoV, Sabine Hazan, and butyrate producing colon species.

Feed them well and you are feeding yourself well too! Vitamin C, D, zinc, inulin, arabinoxylan, and pomegranate peel help support bifidobacterium and butyrate producing species of the microbiome.

Epoch TV had an interview about microbiome risks found by Dr. Sabine Hazan who has a lab and clinic, and in collaboration with Dr. Thomas Borody who has developed fecal transplant therapy. She spent a lot of her own money testing fecal microbiome samples from many people before and after they got CoV infection or injections. She was looking for changes or differences and found a big one. They sought grant money but didn’t get any.

People who didn’t get Covid infections had a lot of bifidobacterium while those who did get sick didn’t have any. Was there a lack that led to the infection risk or was the infection killing them off?

Maybe a bit of both. SARS-CoV-2 is a bacteriophage. However fecal transplant from a healthy donor could help sick patients recover. Drs Hazan and Borody had an excellent recovery rate for patients. Dr. Hazan also used the nutrients zinc, vitamin C and D and added azithromycin (Z-pack) and hydroxychloroquine and later ivermectin. She continued to monitor fecal samples for microbiome health and the medication regime seemed to help - Ivermectin, vitamin C and vitamin D all seemed to help microbiome health in CoV patients.

The injections showed more definitively that the chimeric spike seems harmful to the microbiome. People who had good levels of bifidobacterium prior to injections had levels drop to zero at checks a few months later or six months later. More disturbing was the finding that the microbiome of breast-fed infants of women who had a CoV injection also had no bifidobacterium. Dr. Hazan suspected the spike was causing the microbiome changes possibly acting like a bacteriophage - infecting certain species which can lead to the bacteria dying.

• Dr. Sabine Hazan: The Gut Bacteria That’s Missing in People Who Get Severe COVID (theepochtimes.com)

Aerobic Bifidobacterium - benefits:

“Several functions have been attributed to bifidobacteria, encompassing degradation of non-digestible carbohydrates, protection against pathogens, production of vitamin B, antioxidants, and conjugated linoleic acids, and stimulation of the immune system. During life, the numbers of bifidobacteria decrease from up to 90% of the total colon microbiota in vaginally delivered breast-fed infants to <5% in the colon of adults and they decrease even more in that of elderly as well as in patients with certain disorders such as antibiotic-associated diarrhea, inflammatory bowel disease, irritable bowel syndrome, obesity, allergies, and regressive autism.” (Rivière, et al., 2016)

Anaerobic Butyrate-producing species - benefits of butyrate for the colon:

“Butyrate is an essential metabolite in the human colon, as it is the preferred energy source for the colon epithelial cells, contributes to the maintenance of the gut barrier functions, and has immunomodulatory and anti-inflammatory properties.” (Rivière, et al., 2016)

Inulin and arabinoxylan fiber help promote both bifidobacterium in the small intestine and butyrate producing species in the colon.

Two types of starch promote both butyrate species and bifidobacterium, seemingly in an interactive supportive way referred to as “cross-feeding”. The starches are inulin-type fructans (ITF) and arabinoxylan-oligosaccharides (AXOS). (Rivière, et al., 2016) Bifidobacterium species also seem to work together to digest the AXOS fiber.

“It has been shown that the butyrogenic effects of ITF and AXOS are the result of cross-feeding interactions between bifidobacteria and butyrate-producing colon bacteria, such as Faecalibacterium prausnitzii (clostridial cluster IV) and Anaerostipes, Eubacterium, and Roseburia species (clostridial cluster XIVa). These kinds of interactions possibly favor the co-existence of bifidobacterial strains with other bifidobacteria and with butyrate-producing colon bacteria in the human colon.” (Rivière, et al., 2016)

Food sources of inulin include: chicory root, 41.6 gr., Jerusalem artichokes (aka sunchokes), 18 gr., dandelion greens, 13.5 gr., garlic, 12.5 gr., leeks, 6.5 gr., asparagus, 2.5 gr., wheat bran, 2.5 gr., bananas, 0.5 gr.. (Livestrong.com) *The grams of inulin fiber is per 100 grams of the food, about 3.5 oz. We are more likely to eat 3.5 ounces of Jerusalem artichoke tubers or dandelion greens than wheat bran or chicory root. Asparagus doesn’t have as much as leeks but more people eat them and would eat a half cup compared to a spoonful of wheat bran sprinkled on something else. Onions in general are also a source of inulin and rye and barley are mentioned in another source.

Foragers can go look for burdock and dig up the roots which are starchy and a good source of inulin. The Japanese cultivate burdock root as a favored food called Gobo. Burdock grows in ditches, gets enormous leaves and then grows taller stems with burrs that get caught on clothes or fur. (healthline.com) Foraging identification guide: (ediblewildfood.com) More about the medicinal benefits: Burdock – A Common Weed with Powerful Plant Medicine - The Back Yard Herbalist (thebackyardherbalistschool.com)

Food sources of arabinoxylans include: psyllium, flax seed, bamboo shoots, and all cereal grains including rice.

“Arabinoxylans have been found in all major cereal grains, including rye, wheat, barley, oats, rice, sorghum, maize, millet (Izydorczyk and Biliaderis, 1995), as well as in other plants, such as psyllium (Fischer et al., 2004), flax seed, pangola grass, bamboo shoots, and rye grass.”

Arabinoxylans, M.S. Izydorczyk, in Handbook of Hydrocolloids (Second Edition), 2009.

So far today I have had leeks, garlic, sorghum, rice, and flax seed. I have been eating garlic mustard but the dandelion greens are ready for salad. I cut the leaves smallish and add to other lettuce for a mixed greens salad that is peppery but not too bitter at spring-time. Later they aren’t as tasty. *I had a breakfast salad this morning with dandelion greens, very good.

I think the Bubble Tea memer is onto something. Circa very early CoV outbreak, pre jabs.

Butyrate and Bubble Tea

I have been advocating for butyrate producing species since early outbreak when I thought the Bubble Tea meme was an accurate correlation rather than a spurious one. See webpage: Resistant starch/Butyrate on jenniferdepew.com.

Too much resistant starch a negative? cause of endotoxin production?

A question in the comments of a previous post asked about a concern of resistant starch in the diet leading to endotoxin production - my answer was how about moderation. Too much tapioca pudding can lead to overgrowth and gassiness and maybe some endotoxin too. I don’t know the specifics about that question though.

My typical response: Throw some pomegranate peel at it.

Pomegranate peel extract helps promote beneficial species and is a strong antimicrobial for negative species including Candida albicans yeast and Helicobacter pylorus (cause of stomach ulcers). It also has been found to increase bifidobacterium species in an animal-based study (Neyrinck, et al., 2013; cited by nutraingredients-usa.com) and bonus - pomegranate polyphenols improved endothelial dysfunction when given in combination with chitin-glucan. (Neyrinck, et al., 2019)

• Pomegranate peel extract shows prebiotic potential, 08-Jun-2012 By Stephen Daniells, Polyphenol-rich extracts from pomegranate peel may selectively enhance the growth of potentially beneficial gut bacteria, suggesting prebiotic activity for the extract, says a new study. (nutraingredients-usa.com)

Pomegranate peel extract helps promote an improved Firmicutes/Bacteroidetes ratio among the butyrate producing species too.

And don’t forget the zinc! Vitamin C, D and sunshine too!

Zinc adequacy in the diet is needed to assure healthy microbiome species can grow in both the small intestine and colon. Dr. Hazan did note that vitamin C and D supplements led to microbiome improvement in her patients. She didn’t mention the zinc specifically that I remember.

Bacteriophage spike leading to microbe apoptosis? Better off that way, in my opinion, just support regrowth.

If spike is acting as a bacteriophage and gut microbes are committing apoptosis instead of producing spike, then we need to support regrowth, and keep up on anti-spike strategies - like pomegranate peel! Peru’s pomegranate season is underway currently. Personally, I would rather the microbes commit self-death rather than become spike factories in my gut. When I am feeling worse, some wormwood product has consistently helped me, whether artemisinin extract, Wormwood tea, or Sweet Wormwood extract/tincture that I bought.

Disclaimer: This information is being shared for educational purposes within the guidelines of Fair Use and is not intended to provide individual health guidance.

Reference List

(Neyrinck, et al., 2019) Neyrinck AM, Catry E, Taminiau B, Cani PD, Bindels LB, Daube G, Dessy C, Delzenne NM. Chitin-glucan and pomegranate polyphenols improve endothelial dysfunction. Sci Rep. 2019 Oct 2;9(1):14150. doi: 10.1038/s41598-019-50700-4. PMID: 31578395; PMCID: PMC6775069. https://pubmed.ncbi.nlm.nih.gov/31578395/

(Neyrinck, et al., 2013) Neyrinck AM, Van Hée VF, Bindels LB, De Backer F, Cani PD, Delzenne NM. Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hypercholesterolaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota. Br J Nutr. 2013 Mar 14;109(5):802-9. doi: 10.1017/S0007114512002206. Epub 2012 Jun 7. PMID: 22676910. https://pubmed.ncbi.nlm.nih.gov/22676910/

(Rivière, et al., 2016) Rivière A, Selak M, Lantin D, Leroy F, De Vuyst L. Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut. Front Microbiol. 2016 Jun 28;7:979. doi: 10.3389/fmicb.2016.00979. PMID: 27446020; PMCID: PMC4923077. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923077/

(Su-Min, Dong-Hyun, 2017) Su-Min Lim, Dong-Hyun Kim, Bifidobacterium adolescentis IM38 ameliorates high-fat diet–induced colitis in mice by inhibiting NF-κB activation and lipopolysaccharide production by gut microbiota, (2017), Nutrition Research, 41:86-96, ISSN 0271-5317, https://doi.org/10.1016/j.nutres.2017.04.003 https://www.sciencedirect.com/science/article/abs/pii/S027153171630817X